Therapeutic Potential of Solenopsis invicta Venom: A Scoping Review of Its Bioactive Molecules, Biological Aspects, and Health Applications
Mario Dioguardi, Stefania Cantore, Diego Sovereto, Lorenzo Sanesi, Angelo Martella, Lynn Almasri, Gennaro Musella, Lorenzo Lo Muzio, Andrea Ballini · 2024
Read Therapeutic Potential of Solenopsis invicta Venom: A Scoping Review of Its Bioactive Molecules, Biological Aspects, and Health Applications by Mario Dioguardi, Stefania Cantore, Diego Sovereto, Lorenzo Sanesi, Angelo Martella, Lynn Almasri, Gennaro Musella, Lorenzo Lo Muzio, Andrea Ballini (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11673062.txt.
Description
The red imported fire ant delivers a painful sting, yet its venom carries molecules that kill microbes and may fight tumours. Mario Dioguardi and co-authors scoped the evidence for medical uses of the venom, now that the ant has gained a foothold in Europe. From over twelve thousand papers they kept eleven studies, seven on microbes and four on tumour cells or animals.
The venom's main alkaloid and its four peptides stopped bacterial films from forming, fought fungal infections, and slowed tumour growth in the models tested, partly by switching genes. The authors stress that all evidence is early-stage: no human trials exist. They frame the review as a map for drug hunters, balancing the ant's public-health menace against an unusual pharmacy in its sting.
Catalog record
| CREATOR | Mario Dioguardi, Stefania Cantore, Diego Sovereto, Lorenzo Sanesi, Angelo Martella, Lynn Almasri, Gennaro Musella, Lorenzo Lo Muzio, Andrea Ballini |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 58 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |