The Effect of Moringa oleifera Leaf Extract on C2C12 Myoblast Proliferation and Redox Status Under Oxidative Insult
Roberta Ceci, Mariateresa Maldini, Piergiorgio La Rosa, Laura Sireno, Cristina Antinozzi, Mark E Olson, Ivan Dimauro, Guglielmo Duranti, Vincenzo De Feo, Filomena Nazzaro · 2024
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Description
Roberta Ceci and co-authors test a leaf extract on muscle cells under stress in a 2024 study. Muscle rebuilds after damage when precursor cells, called myoblasts, multiply and mature. Oxidative stress, a flood of reactive molecules such as hydrogen peroxide, kills many of those cells and stalls repair. The extract of moringa leaves is rich in antioxidants and might shield them.
Chemical profiling found the extract loaded with protective compounds, led by two families with long chemical names. In dishes, peroxide threw the cells' redox balance off and killed them; adding the extract restored a key protective ratio, kept more cells alive, and helped wounds in the cell layer close. The authors read the results as early evidence that moringa extract can guard muscle precursors during oxidative attack, a hint for later work on muscle recovery.
Catalog record
| CREATOR | Roberta Ceci, Mariateresa Maldini, Piergiorgio La Rosa, Laura Sireno, Cristina Antinozzi, Mark E Olson, Ivan Dimauro, Guglielmo Duranti, Vincenzo De Feo, Filomena Nazzaro |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 46 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |