Factors influencing vancomycin trough concentration in burn patients: a single center retrospective study
Yan Shi, Zongqi Yin, Qin Zhang, Lei Yi, Yi Dou · 2024
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Description
Yan Shi and co-authors studied this 2024 question in burn care at one hospital in China. The antibiotic vancomycin needs a blood level high enough to fight infection but safe for the patient. Burn patients often miss that target range. The team looked for patient traits that predict where the level lands.
The study covered adults given a fixed dose twice a day. Only 14 of 80 patients reached the target range of 10 to 20 units. The other 66 fell below it. Patients who reached the range had higher levels of a kidney marker and lower levels of a blood protein, albumin. A cutoff near 34.50 for albumin helped split the groups. The results can guide dose choices for burn patients.
Catalog record
| CREATOR | Yan Shi, Zongqi Yin, Qin Zhang, Lei Yi, Yi Dou |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 31 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |