The Combined Use of Triamcinolone and Platelet-Rich Plasma in Equine Metacarpophalangeal Joint Osteoarthritis Treatments: An In Vivo and In Vitro Study
Kübra Guidoni, Elisabetta Chiaradia, Marco Pepe, Antonio Di Meo, Alessia Tognoloni, Matteo Seccaroni, Francesca Beccati · 2024
Read The Combined Use of Triamcinolone and Platelet-Rich Plasma in Equine Metacarpophalangeal Joint Osteoarthritis Treatments: An In Vivo and In Vitro Study by Kübra Guidoni, Elisabetta Chiaradia, Marco Pepe, Antonio Di Meo, Alessia Tognoloni, Matteo Seccaroni, Francesca Beccati (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11672629.txt.
Description
Kübra Guidoni and co-authors test whether platelet-rich plasma can offset the harms of a steroid drug in horse joint osteoarthritis. Triamcinolone cuts joint pain but can hurt cartilage metabolism. Platelet-rich plasma, by contrast, may help cartilage heal. Cell tests came first, then a trial in thirty-two racehorses with fetlock joint disease.
In cell culture, the steroid sharply cut cartilage cell survival, while added plasma prevented that drop and raised cell growth. In horses, both groups flexed better one week after the last treatment. By two weeks, only the combined group kept better flexion, and its lameness scores had also improved. More trials are needed on safety and effect, the authors note.
Catalog record
| CREATOR | Kübra Guidoni, Elisabetta Chiaradia, Marco Pepe, Antonio Di Meo, Alessia Tognoloni, Matteo Seccaroni, Francesca Beccati |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 29 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |