High-Speed Sequential DNA Computing Using a Solid-State DNA Origami Register
Qian Zhang, Mingqiang Li, Yuqing Tang, Jinyan Zhang, Chenyun Sun, Yaya Hao, Jianing Cheng, Xiaodong Xie, Sisi Jia, Hui Lv, Fei Wang, Chunhai Fan · 2024
Read High-Speed Sequential DNA Computing Using a Solid-State DNA Origami Register by Qian Zhang, Mingqiang Li, Yuqing Tang, Jinyan Zhang, Chenyun Sun, Yaya Hao, Jianing Cheng, Xiaodong Xie, Sisi Jia, Hui Lv, Fei Wang, Chunhai Fan (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11672539.txt.
Description
Qian Zhang and eleven co-authors published a molecular computing study in twenty twenty-four on making DNA computers run steps in sequence, quickly. DNA circuits process information through molecular reactions, and origami registers can pass signals between them. Earlier registers could be written only once and moved signals slowly, throttling any multi-step program.
The new register is solid-state: it compresses a circuit's output from three-dimensional solution onto a two-dimensional surface, and it can be rewritten. A hybrid design linking liquid circuits to the surface register cut transfer time to under an hour. A trace amplifier reads stored signals back into solution. The authors say the design enables faster programs and even visual debugging.
Catalog record
| CREATOR | Qian Zhang, Mingqiang Li, Yuqing Tang, Jinyan Zhang, Chenyun Sun, Yaya Hao, Jianing Cheng, Xiaodong Xie, Sisi Jia, Hui Lv, Fei Wang, Chunhai Fan |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 30 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |