Hemodynamic Response to Lipopolysaccharide Infusion and Effect of Meloxicam Administration on Cardiac Function in Donkeys
Francisco J. Mendoza, Antonio Buzon-Cuevas, Raul Aguilera-Aguilera, Carlos A. Gonzalez-De Cara, Adelaida De Las Heras, Alejandro Perez-Ecija · 2024
Read Hemodynamic Response to Lipopolysaccharide Infusion and Effect of Meloxicam Administration on Cardiac Function in Donkeys by Francisco J. Mendoza, Antonio Buzon-Cuevas, Raul Aguilera-Aguilera, Carlos A. Gonzalez-De Cara, Adelaida De Las Heras, Alejandro Perez-Ecija (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11672460.txt.
Description
Francisco Mendoza and co-authors test, in a 2024 veterinary study, how a bacterial toxin hits the donkey heart, and whether a common pain drug can block the harm. Endotoxemia drives the body-wide inflammation that follows colic and gut disease in equines. Horses suffer clear heart and pressure trouble from it, but donkeys had never been tested. Six healthy jennies got a toxin infusion under close watch for six hours.
The toxin raised a heart injury marker in the blood, dropped blood pressure and vein pressure, and weakened the heart's pumping on ultrasound. A dose of meloxicam, an anti-inflammatory, prevented nearly all of it: no injury marker rise, steadier pressure, and a protected heartbeat. The authors propose the drug as a real option for donkeys in this dangerous state.
Catalog record
| CREATOR | Francisco J. Mendoza, Antonio Buzon-Cuevas, Raul Aguilera-Aguilera, Carlos A. Gonzalez-De Cara, Adelaida De Las Heras, Alejandro Perez-Ecija |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 26 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |