Evaluation of Antibiotic Resistance Mechanisms in Gram-Positive Bacteria
Pratiksing Rajput, Kazi S. Nahar, Khondaker Miraz Rahman · 2024
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Description
Pratiksing Rajput, Kazi Nahar, and Khondaker Miraz Rahman wrote this review paper, published in 2024. It explains how Gram-positive bacteria defeat antibiotics, and why the world's health agencies rank some of them as top-priority threats.
Resistance in these bacteria is rising fast, yet the World Health Organization's priority list barely changed between 2017 and 2024, a sign of slow progress on new drugs. The review walks through the main tricks: enzymes that destroy drugs, altered drug targets, walls that keep drugs out, and pumps that throw drugs back. It then covers the resistance playbook of three high-priority germs, including Staphylococcus aureus and Streptococcus pneumoniae. The authors argue that knowing each mechanism is the first step to designing treatments that can beat it.
Catalog record
| CREATOR | Pratiksing Rajput, Kazi S. Nahar, Khondaker Miraz Rahman |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 70 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |