Efficacy of Supratherapeutic Duloxetine Combined With Cognitive-Behavioral Therapy in Severe Treatment-Resistant Obsessive-Compulsive Disorder With Comorbid Depression: A Case Report
Syed Ali Bokhari, Mohamed H Nasr, Yasmeen T Alawadhi · 2024
Read Efficacy of Supratherapeutic Duloxetine Combined With Cognitive-Behavioral Therapy in Severe Treatment-Resistant Obsessive-Compulsive Disorder With Comorbid Depression: A Case Report by Syed Ali Bokhari, Mohamed H Nasr, Yasmeen T Alawadhi (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11671769.txt.
Description
Syed Bokhari, Mohamed Nasr, and Yasmeen Alawadhi report in 2024 a case where very high-dose duloxetine plus therapy breaks a decade of treatment-resistant obsessive-compulsive disorder with depression. The 42-year-old man had tried many drugs and therapy rounds with only partial relief. Standard doses seemed spent.
Baseline scores mark severe depression and marked obsessive symptoms. The dose climbs gradually to 180 milligrams per day under close watch. Within weeks both symptom sets ease a great deal. Gains hold over six months with minimal side effects, and daily function and life quality rise. Scores fall from 28 to 8 on depression and 34 to 12 on obsessive scales. The case hints at a reserve option for stubborn cases.
Catalog record
| CREATOR | Syed Ali Bokhari, Mohamed H Nasr, Yasmeen T Alawadhi |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 18 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |