Connecting dots of long COVID-19 pathogenesis: a vagus nerve- hypothalamic-pituitary- adrenal-mitochondrial axis dysfunction
Marta Camici, Giulia Del Duca, Anna Clelia Brita, Andrea Antinori · 2024
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Description
Marta Camici, Giulia Del Duca, Anna Clelia Brita, and Andrea Antinori propose a linked explanation for long COVID in a 2024 article. Long COVID still lacks a clear cause and a proven treatment. The authors argue the key lies in lasting harm to three systems that calm inflammation. These are reflexes run by the vagus nerve, a hormone axis from brain to adrenal glands, and the energy parts of cells.
They trace how the virus could damage each stage of this linked axis, directly, through immune attack, or by waking dormant viruses. Two chemical messengers get close attention for their shared calming roles. If the calming systems are weak, cell damage from the virus may go unchecked. The authors call for studies of hormone receptor sensitivity in people with long COVID.
Catalog record
| CREATOR | Marta Camici, Giulia Del Duca, Anna Clelia Brita, Andrea Antinori |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 44 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |