Comparative analysis of mineralocorticoid receptor antagonists and renin-angiotensin system inhibitors/angiotensin receptor neprilysin inhibitor in heart failure with mildly reduced ejection fraction

Chia-Chen Lee, David Te-Wei Kuan, Kai-Chun Chang, Zheng-Wei Chen, Jen-Fang Cheng, Ting-Tse Lin, Lian-Yu Lin, Cho-Kai Wu · 2024

Read Comparative analysis of mineralocorticoid receptor antagonists and renin-angiotensin system inhibitors/angiotensin receptor neprilysin inhibitor in heart failure with mildly reduced ejection fraction by Chia-Chen Lee, David Te-Wei Kuan, Kai-Chun Chang, Zheng-Wei Chen, Jen-Fang Cheng, Ting-Tse Lin, Lian-Yu Lin, Cho-Kai Wu (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11671259.txt.

Description

Chia-Chen Lee and co-authors present a 2024 study comparing two heart drug families in patients whose hearts pump at mildly reduced strength. This in-between form of heart failure has fewer proven treatments than the severe form. One family blocks a hormone receptor tied to salt and water, the other blends two blood-pressure mechanisms in one pill.

Using a large Taiwanese hospital database, the team weighed treated patients so the groups compared fairly. The main yardstick combined death from cardiovascular causes with hospital stays for heart failure. The head-to-head evidence helps doctors choose between two plausible add-ons where trial data remain thin, a common frustration in this borderline group.

Catalog record

CREATORChia-Chen Lee, David Te-Wei Kuan, Kai-Chun Chang, Zheng-Wei Chen, Jen-Fang Cheng, Ting-Tse Lin, Lian-Yu Lin, Cho-Kai Wu
YEAR2024
COLLECTIONPAPERS
FORMATTXT
FILE SIZE36 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC11671259

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