One‐Step Nucleic Acid Amplification Analysis of Sentinel Nodes in Endometrial Cancer Versus Ultrastaging: First Long‐Term Follow‐Up Data of Discordant Cases
Jan Kosťun, Khaled M Ismail, Martin Pešta, Robert Slunečko, Petr Stráník, Vendula Smoligová, Jiří Presl · 2024
Read One‐Step Nucleic Acid Amplification Analysis of Sentinel Nodes in Endometrial Cancer Versus Ultrastaging: First Long‐Term Follow‐Up Data of Discordant Cases by Jan Kosťun, Khaled M Ismail, Martin Pešta, Robert Slunečko, Petr Stráník, Vendula Smoligová, Jiří Presl (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11670742.txt.
Description
Jan Kosťun and six co-authors present a 2024 follow-up study on a fast molecular test for cancer spread in womb cancer surgery. During staging, sentinel lymph nodes are checked for tumor. A rapid amplification test can disagree with the painstaking microscopic method called ultrastaging. The authors tracked the patients whose results clashed, test positive but microscope negative, for a median of nearly seven years.
Twelve such patients were found from the original fifty-eight. Three saw their cancer return; two recurrences were in lymph nodes and both patients died. A third had a lone lung spot that was removed, leaving her disease-free. The group's recurrence rate matched higher-risk categories, above what the microscope result alone predicted. The authors also note that harmless gland fragments in nodes do not seem to fool the molecular test. The findings argue the rapid test's positives deserve respect.
Catalog record
| CREATOR | Jan Kosťun, Khaled M Ismail, Martin Pešta, Robert Slunečko, Petr Stráník, Vendula Smoligová, Jiří Presl |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 21 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |