Targeting caspase-8: a new strategy for combating hepatocellular carcinoma
Haoran Chen, Yumeng Lin, Jie Chen, Xuemei Luo, Yubo Kan, Yuqi He, Renhe Zhu, Jiahui Jin, Dongxuan Li, Yi Wang, Zhongyu Han · 2024
Read Targeting caspase-8: a new strategy for combating hepatocellular carcinoma by Haoran Chen, Yumeng Lin, Jie Chen, Xuemei Luo, Yubo Kan, Yuqi He, Renhe Zhu, Jiahui Jin, Dongxuan Li, Yi Wang, Zhongyu Han (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11669555.txt.
Description
An enzyme that helps decide how cells die could become a target against the most common liver cancer, argues a 2024 review by Haoran Chen and co-authors. The enzyme, caspase-8, sits at the crossing of several death programs and also shapes inflammation and the immune cells around a tumor.
The review maps its roles in four forms of cell death, then follows its ties to liver cancer growth, spread, and drug resistance. When the enzyme's balance slips, tumors gain. The authors weigh ways to aim drugs at it, arguing that its central place makes it promising but also delicate to disturb.
Catalog record
| CREATOR | Haoran Chen, Yumeng Lin, Jie Chen, Xuemei Luo, Yubo Kan, Yuqi He, Renhe Zhu, Jiahui Jin, Dongxuan Li, Yi Wang, Zhongyu Han |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 60 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |