Genotype-negative multiple endocrine neoplasia type 1 with prolactinoma, hyperparathyroidism, and subclinical Cushing’s syndrome accompanied by hyperglycemia: a case report
Haremaru Kubo, Ryota Wada, Naohiro Sekikawa, Yasuhisa Nomura, Mutsuo Yamada, Minoru Inoue, Naoki Hattori, Yuto Yamazaki, Kazuhiro Sugimoto · 2024
Read Genotype-negative multiple endocrine neoplasia type 1 with prolactinoma, hyperparathyroidism, and subclinical Cushing’s syndrome accompanied by hyperglycemia: a case report by Haremaru Kubo, Ryota Wada, Naohiro Sekikawa, Yasuhisa Nomura, Mutsuo Yamada, Minoru Inoue, Naoki Hattori, Yuto Yamazaki, Kazuhiro Sugimoto (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11669518.txt.
Description
Haremaru Kubo and co-authors report the case of a 56-year-old woman whose hormone disorders matched a syndrome her gene tests said she did not have, in a 2024 case report. The syndrome, called MEN1, causes tumors in several hormone glands and usually runs in families through one gene. This patient had no family history and no harmful change in that gene.
She had a pituitary tumor that overproduced prolactin, an overactive parathyroid gland, and an adrenal tumor making cortisol, with severe diabetes on top. A drug shrank the prolactin problem and her diabetes medicine could later be stopped. Surgery removed the parathyroid and adrenal growths, and a thyroid tumor taken at the same time proved to be a spreading cancer. The case shows the syndrome's full picture can arise without the classic gene fault.
Catalog record
| CREATOR | Haremaru Kubo, Ryota Wada, Naohiro Sekikawa, Yasuhisa Nomura, Mutsuo Yamada, Minoru Inoue, Naoki Hattori, Yuto Yamazaki, Kazuhiro Sugimoto |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 25 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |