Shifts in naturalistic behaviors induced by early social isolation stress are associated with adult binge-like eating in female rats
Timothy B. Simon, Julio Sierra, Arianna Williams, Giara Wright, Allison Rhee, Julius Horn, John Lou, Fransua Sharafeddin, Perla Ontiveros-Ángel, Johnny D. Figueroa · 2024
Read Shifts in naturalistic behaviors induced by early social isolation stress are associated with adult binge-like eating in female rats by Timothy B. Simon, Julio Sierra, Arianna Williams, Giara Wright, Allison Rhee, Julius Horn, John Lou, Fransua Sharafeddin, Perla Ontiveros-Ángel, Johnny D. Figueroa (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11669510.txt.
Description
Timothy Simon and co-authors track how social isolation in young rats reshapes everyday behavior and later eating. Their 2024 study follows binge eating, a coping pattern tied to early life stress that often surfaces only in adulthood. Female rats lived paired or alone and were filmed weekly in home cages for seven weeks.
Software scored ten natural behaviors automatically. Isolation shifted the overall behavior profile, hitting sniffing, rearing, jumping, and twitching hardest. Isolated rats also showed stronger emotional reactions as adults. One teen behavior, twitching, predicted how much fatty food the adult rats would binge. The authors suggest home cage monitoring could flag at-risk animals early.
Catalog record
| CREATOR | Timothy B. Simon, Julio Sierra, Arianna Williams, Giara Wright, Allison Rhee, Julius Horn, John Lou, Fransua Sharafeddin, Perla Ontiveros-Ángel, Johnny D. Figueroa |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 61 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |