Exploring the Influence of Genetic Single-Nucleotide Polymorphism (SNPs) on Endodontic Pathologies: A Comprehensive Review
Ali M Falatah, Salihah A Alturki, Abdulatif I Aldahami, Nourh A Alrashidi, Yahya Sinnah, Rowaida M Aldgeel, Khalid Z Alanazi, Amira S Alkhaled, Talal S ALjuaid, Naif H Alotaibi, Worod J Altwijri · 2024
Read Exploring the Influence of Genetic Single-Nucleotide Polymorphism (SNPs) on Endodontic Pathologies: A Comprehensive Review by Ali M Falatah, Salihah A Alturki, Abdulatif I Aldahami, Nourh A Alrashidi, Yahya Sinnah, Rowaida M Aldgeel, Khalid Z Alanazi, Amira S Alkhaled, Talal S ALjuaid, Naif H Alotaibi, Worod J Altwijri (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11669393.txt.
Description
Falatah and co-authors review how single-letter gene variants shape diseases of the tooth pulp and root tip, in a 2024 paper. Infections start these conditions, but genes help decide who gets sick and how badly. The review gathers studies linking such variants to pulpitis, root abscesses, treatment outcomes, and related dental problems. Attention centers on genes that run inflammation and tissue breakdown.
Variants in interleukin genes, which steer immune signaling, tracked with higher risk of inflammation around the root tip. Variants in matrix metalloproteinase genes, whose products chew through tissue, were tied to lesion damage. The authors frame dental disease as a gene-environment interplay, not germs alone. Genetic insight could one day guide who needs closer watch after root canal care.
Catalog record
| CREATOR | Ali M Falatah, Salihah A Alturki, Abdulatif I Aldahami, Nourh A Alrashidi, Yahya Sinnah, Rowaida M Aldgeel, Khalid Z Alanazi, Amira S Alkhaled, Talal S ALjuaid, Naif H Alotaibi, Worod J Altwijri |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 41 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |