A triple protein-based ELISA for differential detection of ASFV antibodies
Shuai Zhang, Yuzhu Zuo, Wenyuan Gu, Yunhuan Zhao, Ying Liu, Jinghui Fan · 2024
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Description
Shuai Zhang and co-authors develop a blood test that tells not just whether a pig has African swine fever, but which form of the virus it carries. The disease is severe, spreads fast, and has no vaccine or cure, so early detection carries the burden of control. New low-strength strains missing genes have appeared, and standard kits cannot separate them from the wild virus, which muddies outbreak response.
Their test uses three virus proteins, each flagging one part of the virus's makeup. In checks against other pig diseases it showed no cross-reactions, and it could read samples diluted eight-hundred-fold. On 59 farm samples it sorted wild-type infections from gene-deleted ones and matched gene-based testing in 58 cases. The authors say the test gives farms and officials a clearer picture when they decide how to contain an outbreak.
Catalog record
| CREATOR | Shuai Zhang, Yuzhu Zuo, Wenyuan Gu, Yunhuan Zhao, Ying Liu, Jinghui Fan |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 43 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |