Hyperbaric Oxygen Therapy Improved Neovascularisation Following Limb Ischaemia—The Role of ROS Mitigation
You‐Cheng Lin, Jhih‐Yuan Shih, Yu‐Wen Lin, Ko‐Chi Niu, Chon‐Seng Hong, Zhih‐Cherng Chen, Shin‐Chen Pan, Tzu‐Yen Chang, Wei‐Chih Kan, Wei‐Ting Chang · 2024
Read Hyperbaric Oxygen Therapy Improved Neovascularisation Following Limb Ischaemia—The Role of ROS Mitigation by You‐Cheng Lin, Jhih‐Yuan Shih, Yu‐Wen Lin, Ko‐Chi Niu, Chon‐Seng Hong, Zhih‐Cherng Chen, Shin‐Chen Pan, Tzu‐Yen Chang, Wei‐Chih Kan, Wei‐Ting Chang (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11669187.txt.
Description
You-Cheng Lin and nine co-authors show that oxygen under pressure boosts new vessel growth after limb blood loss, in a study from 2024. Poor blood flow to a limb triggers low oxygen stress, and extra oxygen might help vessels regrow. The role of harmful oxygen byproducts in that response was unclear.
Mice treated with pure oxygen under pressure for five days after limb surgery grew vessels better and showed less of the harmful byproducts than untreated mice. In dishes, the treatment rescued vessel cells starved of oxygen and sugar, restoring growth and tube forming. Growth signals and protective proteins rose in step with the benefit.
Catalog record
| CREATOR | You‐Cheng Lin, Jhih‐Yuan Shih, Yu‐Wen Lin, Ko‐Chi Niu, Chon‐Seng Hong, Zhih‐Cherng Chen, Shin‐Chen Pan, Tzu‐Yen Chang, Wei‐Chih Kan, Wei‐Ting Chang |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 32 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |