Evaluation of the covariation between leukotriene B4, prostaglandin E2, and hematologic inflammatory parameters in a canine pentylenetetrazole-induced seizure model
Yoonhoi Koo, Taesik Yun, Yeon Chae, Dohee Lee, Hakhyun Kim, Mhan-Pyo Yang, Byeong-Teck Kang · 2024
Read Evaluation of the covariation between leukotriene B4, prostaglandin E2, and hematologic inflammatory parameters in a canine pentylenetetrazole-induced seizure model by Yoonhoi Koo, Taesik Yun, Yeon Chae, Dohee Lee, Hakhyun Kim, Mhan-Pyo Yang, Byeong-Teck Kang (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11668773.txt.
Description
Yoonhoi Koo and co-authors track inflammation markers after induced seizures in dogs, in a research paper from 2024. Seizures can both stem from and cause brain inflammation. Blood markers that shift after a single seizure could aid diagnosis and care, but their time course in a controlled model was unmapped.
Five healthy beagle dogs received a drug infusion until a full convulsion occurred. Blood was sampled over two windows, from minutes to two days after the seizure. Ratios built from white cell and protein counts shifted at set times. Two lipid mediators were also measured by lab assay. The pattern shows which markers move early and which move late after a seizure.
Catalog record
| CREATOR | Yoonhoi Koo, Taesik Yun, Yeon Chae, Dohee Lee, Hakhyun Kim, Mhan-Pyo Yang, Byeong-Teck Kang |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 36 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |