Wild Brazilian yellow fever virus infection in Syrian hamsters (Mesocricetus auratus): Clinical and histopathological analyses
Fernanda de Oliveira Bottino, Barbara Cristina Euzebio Pereira Dias de Oliveira, João Paulo Rodrigues dos Santos, Mariana Barata Viana Tiradentes, Yuli Rodrigues Maia de Souza, Tainah Silva Galdino de Paula, Hyago da Silva Medeiros Elido, Isabele Barbieri dos Santos, Ieda Pereira Ribeiro, Myrna Cris · 2024
Read Wild Brazilian yellow fever virus infection in Syrian hamsters (Mesocricetus auratus): Clinical and histopathological analyses by Fernanda de Oliveira Bottino, Barbara Cristina Euzebio Pereira Dias de Oliveira, João Paulo Rodrigues dos Santos, Mariana Barata Viana Tiradentes, Yuli Rodrigues Maia de Souza, Tainah Silva Galdino de Paula, Hyago da Silva Medeiros Elido, Isabele Barbieri dos Santos, Ieda Pereira Ribeiro, Myrna Cris (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11667703.txt.
Description
Yellow fever still erupts in Brazil, and lab animals that mimic human infection are needed to study new virus strains. Fernanda de Oliveira Bottino and a large team of co-authors infected Syrian hamsters in 2024 with two wild Brazilian virus isolates taken from dead howler monkeys.
One isolate, from a 2008 outbreak, made the hamsters lose weight steadily and kept virus in their blood for at least a week, with damage showing in liver, spleen, and pancreas. The other, from 2019, was cleared within a week. A vaccine strain caused no illness at all. The contrast shows that hamsters resist some wild strains yet sicken under others, which sharpens the model for testing the virus's gut-seeking behavior.
Catalog record
| CREATOR | Fernanda de Oliveira Bottino, Barbara Cristina Euzebio Pereira Dias de Oliveira, João Paulo Rodrigues dos Santos, Mariana Barata Viana Tiradentes, Yuli Rodrigues Maia de Souza, Tainah Silva Galdino de Paula, Hyago da Silva Medeiros Elido, Isabele Barbieri dos Santos, Ieda Pereira Ribeiro, Myrna Cris |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 40 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |