Prognostic Value of N1/N2 Neutrophils Heterogeneity and Tertiary Lymphoid Structure in Hepatocellular Carcinoma Patients

Yanfei Lang, Weiwei Fu, Wei Xu, Chao Ma, Xiuyun Tian, Chunyi Hao, Shigang Ding · 2024

Read Prognostic Value of N1/N2 Neutrophils Heterogeneity and Tertiary Lymphoid Structure in Hepatocellular Carcinoma Patients by Yanfei Lang, Weiwei Fu, Wei Xu, Chao Ma, Xiuyun Tian, Chunyi Hao, Shigang Ding (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11667523.txt.

Description

Yanfei Lang and co-authors weigh neutrophil types and lymphoid structures for outlook in liver cancer in a 2024 study. Tumor neutrophils can fight tumors in an N1 form or aid them in an N2 form, and lymphoid clusters also shape immunity.

Tissue from close to eighty resected patients was stained to map both features in tumor and nearby tissue. In tumor tissue, more N1 cells tied to better outlook, while nearby patterns flipped. Mature lymphoid structures nearby also favored survival. Most neutrophils sat outside the lymphoid clusters. Combined patterns sharpened prognosis beyond single marks. The work guides immune-based risk grading after liver cancer surgery.

Catalog record

CREATORYanfei Lang, Weiwei Fu, Wei Xu, Chao Ma, Xiuyun Tian, Chunyi Hao, Shigang Ding
YEAR2024
COLLECTIONPAPERS
FORMATTXT
FILE SIZE38 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC11667523

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