A crucial new aspect of cardiac morphogenesis: endocardial hematopoiesis
Norika Liu, Atsushi Nakano · 2024
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Description
Norika Liu and Atsushi Nakano wrote a 2024 opinion piece on how the heart forms before birth. The inner lining of the early heart, the endocardium, was long known to help build the heart valves and walls. New work shows that these same lining cells can also turn into blood cells, a switch the authors call endocardial hematopoiesis.
The piece sums up studies, many in mouse and fly embryos, that trace this blood-forming role. It argues that blood making is not limited to the yolk sac and one other early site, as once thought. For readers, the value is a fresh view of how the heart and blood systems grow up together.
Catalog record
| CREATOR | Norika Liu, Atsushi Nakano |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 15 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |