International consensus to define outcomes for trials of chemoradiotherapy for anal cancer (CORMAC-2): defining the outcomes from the CORMAC core outcome set

Robert Samuel, Stephen R Knight, Richard Adams, Prajnan Das, Jennifer Dorth, David Finch, Marianne G Guren, Maria A Hawkins, Susan Moug, Lakshmi Rajdev, David Sebag-Montefiore, Andrew G Renehan, Rebecca Fish, plus the CORMAC-2 collaborators · 2024

Read International consensus to define outcomes for trials of chemoradiotherapy for anal cancer (CORMAC-2): defining the outcomes from the CORMAC core outcome set by Robert Samuel, Stephen R Knight, Richard Adams, Prajnan Das, Jennifer Dorth, David Finch, Marianne G Guren, Maria A Hawkins, Susan Moug, Lakshmi Rajdev, David Sebag-Montefiore, Andrew G Renehan, Rebecca Fish, plus the CORMAC-2 collaborators (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11667046.txt.

Description

Robert Samuel and the CORMAC-2 collaborators hammer out shared meanings for anal cancer trial results, in a two thousand twenty-four consensus paper. Trials of chemoradiotherapy for anal squamous cell carcinoma report results so variably that results resist comparison.

An earlier project had agreed a nineteen-result core set across disease activity, survival, toxicity, and life impact. This phase standardized meanings for the eleven disease activity and survival results. Current meanings were harvested by systematic review, tested in a two-round Delphi survey of fifty-one experts from thirteen countries, and ratified at a consensus meeting. Uniform meanings, the authors argue, make the core set usable in real trials and improve choice data.

Catalog record

CREATORRobert Samuel, Stephen R Knight, Richard Adams, Prajnan Das, Jennifer Dorth, David Finch, Marianne G Guren, Maria A Hawkins, Susan Moug, Lakshmi Rajdev, David Sebag-Montefiore, Andrew G Renehan, Rebecca Fish, plus the CORMAC-2 collaborators
YEAR2024
COLLECTIONPAPERS
FORMATTXT
FILE SIZE45 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC11667046

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