Protective Effects of Polysaccharides From Sargassum hemiphyllum (Turner) C. Agardh Against Alcohol‐Induced LO2 Cell Damage

Yuxuan Liang, Zhuo Wang, Rui Li, Saiyi Zhong, Xiaofei Liu, Jianping Chen · 2024

Read Protective Effects of Polysaccharides From Sargassum hemiphyllum (Turner) C. Agardh Against Alcohol‐Induced LO2 Cell Damage by Yuxuan Liang, Zhuo Wang, Rui Li, Saiyi Zhong, Xiaofei Liu, Jianping Chen (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11666916.txt.

Description

Yuxuan Liang and co-authors report a cell study, published in 2024, on whether seaweed sugars can shield liver cells from alcohol damage. The sugars, called polysaccharides, come from a brown seaweed used in coastal food traditions. The team built an alcohol injury model in a human liver cell line, exposing the cells to strong ethanol for several hours.

Cells treated with the seaweed sugars survived far better than unprotected ones, with survival climbing as dose rose. Inside the cells, harmful oxygen radicals fell, protective glutathione rose, and liver enzymes stayed inside instead of leaking out. Protein tests showed the treatment defended a master antioxidant switch. The authors present the seaweed extract as a candidate protector against alcoholic liver injury.

Catalog record

CREATORYuxuan Liang, Zhuo Wang, Rui Li, Saiyi Zhong, Xiaofei Liu, Jianping Chen
YEAR2024
COLLECTIONPAPERS
FORMATTXT
FILE SIZE36 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC11666916

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