Synergistic Effect and Mechanism of Combined Astaxanthin and Curcumin Administration on Ovarian Function in PCOS Mice
Gao Zhang, Man He, Zun Wang, Jinrong Zheng, Dan Zhao, Li Nie, Dongzhi Yuan, Ziyu Zhao, Wei Wang, Limin Yue · 2024
Read Synergistic Effect and Mechanism of Combined Astaxanthin and Curcumin Administration on Ovarian Function in PCOS Mice by Gao Zhang, Man He, Zun Wang, Jinrong Zheng, Dan Zhao, Li Nie, Dongzhi Yuan, Ziyu Zhao, Wei Wang, Limin Yue (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11666913.txt.
Description
Gao Zhang, Man He, and their co-authors tested two natural compounds, alone and together, on ovarian function in mice with a hormone disorder. Their 2024 study models polycystic ovary syndrome, which disrupts cycles and fertility. Fifty young female mice were split into five groups: healthy controls, untreated model mice, and model mice given astaxanthin, curcumin, or both.
The team tracked sex hormone levels, cycle patterns, follicle growth, and egg release rates. Markers of oxidative stress and inflammation were also measured. Model mice showed scrambled cycles, cyst like ovaries, off balance hormones and blood fats, and raised stress and inflammation signals. Treatment effects are compared across the groups to judge whether the pair beats each compound alone.
Catalog record
| CREATOR | Gao Zhang, Man He, Zun Wang, Jinrong Zheng, Dan Zhao, Li Nie, Dongzhi Yuan, Ziyu Zhao, Wei Wang, Limin Yue |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 29 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |