Chemopreventive and Chemotherapeutic Potential of Betulin and Betulinic Acid: Mechanistic Insights From In Vitro, In Vivo and Clinical Studies
Elifsu Nemli, Beyza Saricaoglu, Celale Kirkin, Gulay Ozkan, Esra Capanoglu, Solomon Habtemariam, Javad Sharifi‐Rad, Daniela Calina · 2024
Read Chemopreventive and Chemotherapeutic Potential of Betulin and Betulinic Acid: Mechanistic Insights From In Vitro, In Vivo and Clinical Studies by Elifsu Nemli, Beyza Saricaoglu, Celale Kirkin, Gulay Ozkan, Esra Capanoglu, Solomon Habtemariam, Javad Sharifi‐Rad, Daniela Calina (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11666818.txt.
Description
Elifsu Nemli and co-authors review two birch bark compounds for their power to prevent and treat cancer. Their 2024 review spans cell tests, animal work, and human trials for betulin and its acid form. Both compounds also show action against viruses and swelling in past work.
The chief anti-cancer path is forced cell death, aimed more at cancer cells than at healthy ones. Strength of effect swings with cancer type, dose, source, time, and how the drug is carried. The review sorts a wide and scattered record into one map of what is known. Human dose proof is still missing, the authors note, so careful trials must come before clinic use.
Catalog record
| CREATOR | Elifsu Nemli, Beyza Saricaoglu, Celale Kirkin, Gulay Ozkan, Esra Capanoglu, Solomon Habtemariam, Javad Sharifi‐Rad, Daniela Calina |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 42 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |