Emergence of Omicron FN.1 a descendent of BQ.1.1 in Botswana
Wonderful T Choga, Emanuele Gustani-Buss, Houriiyah Tegally, Dorcas Maruapula, Xiaoyu Yu, Monika Moir, Boitumelo J L Zuze, San Emmanuel James, Nokuthula S Ndlovu, Kedumetse Seru, Patience Motshosi, Alexandra Blenkinsop, Irene Gobe, Cheryl Baxter, Justen Manasa, Shahin Lockman, Roger Shapiro, Joseph · 2024
Read Emergence of Omicron FN.1 a descendent of BQ.1.1 in Botswana by Wonderful T Choga, Emanuele Gustani-Buss, Houriiyah Tegally, Dorcas Maruapula, Xiaoyu Yu, Monika Moir, Boitumelo J L Zuze, San Emmanuel James, Nokuthula S Ndlovu, Kedumetse Seru, Patience Motshosi, Alexandra Blenkinsop, Irene Gobe, Cheryl Baxter, Justen Manasa, Shahin Lockman, Roger Shapiro, Joseph (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11666700.txt.
Description
Wonderful Choga and co-authors report a new Omicron sublineage found in Botswana in a 2024 paper. The lineage, named FN.1, descends from the BQ.1.1 branch of the virus that causes COVID-19. It surfaced in December 2022 as a tight cluster of genomes from the Greater Gaborone district, in both linked and unlinked cases.
Searching about sixteen million public sequences found only eighty-seven FN.1 cases worldwide by late September 2023, split among Botswana, South Africa, and the United Kingdom. Family-tree analysis placed the group's common ancestor in October 2022 and pointed to Botswana as the likely origin. The lineage carries two changes in the spike protein. Despite wide sequencing, FN.1 stayed rare, a pattern the authors use to show the value of local genome surveillance.
Catalog record
| CREATOR | Wonderful T Choga, Emanuele Gustani-Buss, Houriiyah Tegally, Dorcas Maruapula, Xiaoyu Yu, Monika Moir, Boitumelo J L Zuze, San Emmanuel James, Nokuthula S Ndlovu, Kedumetse Seru, Patience Motshosi, Alexandra Blenkinsop, Irene Gobe, Cheryl Baxter, Justen Manasa, Shahin Lockman, Roger Shapiro, Joseph |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 50 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |