Revolutionary drug repositioning: the preventive and therapeutic potential of metformin and other antidiabetic drugs in age-related macular degeneration
Yating Zhou, Fei Xue · 2024
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Description
Yating Zhou and Fei Xue review whether diabetes drugs could be reused to prevent or treat age-related macular degeneration, a leading cause of blindness in older people. Their 2024 paper notes that the standard therapy, eye injections that block blood vessel growth, is costly and needs frequent visits, which many patients struggle to keep up with over time.
Among the drugs reviewed, metformin looks most promising, linked to lower disease risk even at low total doses. Two other drug families carry real downsides, from low blood sugar to heart risks and eye swelling. The review weighs each drug's benefits, harms, and likely paths of action.
Catalog record
| CREATOR | Yating Zhou, Fei Xue |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 25 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |