The Bacterial Biofilms: Formation, Impacts, and Possible Management Targets in the Healthcare System
Eric Omori Omwenga, Silas Onyango Awuor · 2024
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Description
Eric Omori Omwenga and Silas Onyango Awuor wrote this 2024 review on bacterial biofilms, the slime cities microbes build on surfaces, and why hospitals struggle against them. Bacteria living in biofilms gain shelter from both antibiotics and the immune system, turning treatable infections chronic. The strategy is ancient, older than complex life, and widespread across species.
The review traces how biofilms form, how chemical chatter called quorum sensing coordinates them, and how scarcity and harsh conditions trigger construction. Their inner microenvironments dilute drug action and hide residents from immune patrols. The authors survey management targets within the health system, favoring antivirulence ideas that disarm bacteria rather than kill them outright, easing the pressure that breeds resistance. Their closing note is humility: for all their clinical weight, much about how biofilms assemble remains unknown.
Catalog record
| CREATOR | Eric Omori Omwenga, Silas Onyango Awuor |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 39 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |