UDP-glucuronosyltransferases 2A3 as a biomarker for ulcerative colitis and colon cancer

Hao Chen · 2024

Read UDP-glucuronosyltransferases 2A3 as a biomarker for ulcerative colitis and colon cancer by Hao Chen (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11663933.txt.

Description

Hao Chen names a gene as a marker for ulcerative colitis and colon cancer, in work from twenty twenty-four. Ulcerative colitis harms quality of life and raises colon cancer risk. Early diagnosis and fast action matter for both diseases.

Chen mined public gene data from active colitis cases and used machine learning to pick marker genes. One gene, UGT2A3, stood out with high accuracy in training and outside check sets. The gene was far lower in colon cancer tissue than in healthy tissue. Its level linked to cancer type and to patient survival times. Immune cell patterns also tied to the gene. The author offers it as a diagnostic and outlook marker for both diseases.

Catalog record

CREATORHao Chen
YEAR2024
COLLECTIONPAPERS
FORMATTXT
FILE SIZE21 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC11663933

Browse the full library · About the Tower of Babel