Decoding the enigma: unveiling the transmission characteristics of waterfowl-associated blaNDM-5-positive Escherichia coli in select regions of China
Shaqiu Zhang, Yanxi Shu, Zhechen Yang, Zhijun Zhong, Mingshu Wang, Renyong Jia, Shun Chen, Mafeng Liu, Dekang Zhu, Xinxin Zhao, Ying Wu, Qiao Yang, Juan Huang, Xumin Ou, Di Sun, Bin Tian, Zhen Wu, Yu He, Anchun Cheng · 2024
Read Decoding the enigma: unveiling the transmission characteristics of waterfowl-associated blaNDM-5-positive Escherichia coli in select regions of China by Shaqiu Zhang, Yanxi Shu, Zhechen Yang, Zhijun Zhong, Mingshu Wang, Renyong Jia, Shun Chen, Mafeng Liu, Dekang Zhu, Xinxin Zhao, Ying Wu, Qiao Yang, Juan Huang, Xumin Ou, Di Sun, Bin Tian, Zhen Wu, Yu He, Anchun Cheng (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11663885.txt.
Description
Shaqiu Zhang and colleagues trace a last-resort drug resistance gene through ducks and geese in China, in this study from twenty twenty-four. The gene, blaNDM-5, breaks carbapenem antibiotics, the drugs held back for the worst infections. Its carrier here is Escherichia coli, a common gut germ and a sentinel for resistance spread.
From four hundred thirty-one droppings samples across five provinces, the team grew one hundred three positive strains, every one resistant to many drugs. The gene rode on plasmids, the small DNA circles bacteria trade like cards, which makes spread fast and stable. Carrying it cost the bacteria some fitness, yet the enzyme worked strongly. One strain trained on rising drug doses became vastly harder to kill, and stayed that way. The authors warn that farm waterfowl are a live conduit for this gene.
Catalog record
| CREATOR | Shaqiu Zhang, Yanxi Shu, Zhechen Yang, Zhijun Zhong, Mingshu Wang, Renyong Jia, Shun Chen, Mafeng Liu, Dekang Zhu, Xinxin Zhao, Ying Wu, Qiao Yang, Juan Huang, Xumin Ou, Di Sun, Bin Tian, Zhen Wu, Yu He, Anchun Cheng |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 54 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |