Association between polypharmacy and the long-term prescription of hypnotics in Japan: a retrospective cross-sectional study
Munehiro Komatsu, Masahiro Takeshima, Kazuhisa Yoshizawa, Masaya Ogasawara, Mizuki Kudo, Eru Miyakoshi, Yu Itoh, Nana Shibata, Naoko Ayabe, Kazuo Mishima · 2024
Read Association between polypharmacy and the long-term prescription of hypnotics in Japan: a retrospective cross-sectional study by Munehiro Komatsu, Masahiro Takeshima, Kazuhisa Yoshizawa, Masaya Ogasawara, Mizuki Kudo, Eru Miyakoshi, Yu Itoh, Nana Shibata, Naoko Ayabe, Kazuo Mishima (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11663738.txt.
Description
Komatsu and co-authors link two habits in sleeping-pill prescribing in Japan: taking several hypnotics at once, and staying on them for years. From a large claims database they took 112,256 adults prescribed hypnotics, about a third of whom received two or more at once. The team then asked how prescription length related to that stacking.
The longer the prescription history, the stronger the link. People prescribed for four to six months were slightly more likely to stack; those on hypnotics for thirteen to twenty-four months had over three times the odds. The authors suggest starting with a single drug, and keeping courses short, to stop the two habits feeding each other.
Catalog record
| CREATOR | Munehiro Komatsu, Masahiro Takeshima, Kazuhisa Yoshizawa, Masaya Ogasawara, Mizuki Kudo, Eru Miyakoshi, Yu Itoh, Nana Shibata, Naoko Ayabe, Kazuo Mishima |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 52 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |