Exploring the role of NLRP3 infalmmasome in diabetes: a literature review and bibliometric analysis

Yi Tan, Shaotao Chen, Tianjiao Gao, Sixian Wang, Xinfeng Zhou, Mingjun Liu · 2024

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Description

Diabetes care increasingly looks through the lens of inflammation, and one suspect is the NLRP3 inflammasome, a protein complex that ignites inflammatory signals. Six authors mapped a decade of research on its role in diabetes using bibliometric methods, counting and clustering 1,373 papers from 2014 to 2023.

China, the United States, and Italy produced most of the work, and three Chinese medical universities led the institution list. Keyword clusters sorted the field into four fronts: links to inflammatory diseases, cell-level disease mechanisms, treatment approaches, and fiery cell death called pyroptosis. Recent hot terms cluster around the heart, tissue damage, and diabetic kidney disease. The authors chart where the field has been and predict that pyroptosis and diabetes complications will draw the next wave of attention.

Catalog record

CREATORYi Tan, Shaotao Chen, Tianjiao Gao, Sixian Wang, Xinfeng Zhou, Mingjun Liu
YEAR2024
COLLECTIONPAPERS
FORMATTXT
FILE SIZE43 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC11663631

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