Single-pulse transcranial magnetic stimulation of the dorsolateral prefrontal cortex does not directly affect muscle sympathetic nerve activity in humans
Brendan McCarthy, Gianni Sesa-Ashton, Donggyu Rim, Luke A Henderson, Vaughan G Macefield · 2024
Read Single-pulse transcranial magnetic stimulation of the dorsolateral prefrontal cortex does not directly affect muscle sympathetic nerve activity in humans by Brendan McCarthy, Gianni Sesa-Ashton, Donggyu Rim, Luke A Henderson, Vaughan G Macefield (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11663512.txt.
Description
Brendan McCarthy and four co-authors tested whether magnetic pulses to a front brain area can spark nerve bursts to muscles, in twenty twenty-four. The area, the dorsolateral prefrontal cortex, is a common target in treating low mood. Earlier work with alternating current had partly entrained the nerve signal to the stimulus. Here, twelve volunteers had their leg nerve recorded while single pulses were delivered at several strengths.
Pulses went to the target area, to the motor cortex, and to the shoulder, across a range of strengths. No setting changed burst rate or burst share. Most pulse trains in fact lowered burst rates from baseline, wherever they were aimed. The authors read that as an arousal-driven calming of the signal, not an effect of the target area. They conclude the area can tune the signal but cannot directly fire bursts.
Catalog record
| CREATOR | Brendan McCarthy, Gianni Sesa-Ashton, Donggyu Rim, Luke A Henderson, Vaughan G Macefield |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 49 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |