Biotechnological Interventions for the Production of Subunit Vaccines Against Group A Rotavirus

Mukta Prajapati, Pooja Malik, Astha Sinha, Honey Yadav, Yachna K. Jaiwal, Yogesh K. Ahlawat, Darshna Chaudhary, Ranjana Jaiwal, Nisha Sharma, Pawan K. Jaiwal, Vijay K. Chattu · 2024

Read Biotechnological Interventions for the Production of Subunit Vaccines Against Group A Rotavirus by Mukta Prajapati, Pooja Malik, Astha Sinha, Honey Yadav, Yachna K. Jaiwal, Yogesh K. Ahlawat, Darshna Chaudhary, Ranjana Jaiwal, Nisha Sharma, Pawan K. Jaiwal, Vijay K. Chattu (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11662099.txt.

Description

Mukta Prajapati and co-authors review new biotech routes to subunit vaccines for group A rotavirus in a 2024 paper. The virus is a top cause of severe gut illness in infants and young children worldwide. Live vaccines exist, but they work less well in low income areas, raise safety worries for weak immune systems, and need cold storage.

Subunit vaccines use single viral proteins, which makes them safer and more flexible. The review covers making those proteins in bacteria, yeast, insect, mammal, and plant systems for scale and low cost. It also covers design tweaks, boosters, and delivery gains. Some candidates, plus particle based forms, near market readiness.

Catalog record

CREATORMukta Prajapati, Pooja Malik, Astha Sinha, Honey Yadav, Yachna K. Jaiwal, Yogesh K. Ahlawat, Darshna Chaudhary, Ranjana Jaiwal, Nisha Sharma, Pawan K. Jaiwal, Vijay K. Chattu
YEAR2024
COLLECTIONPAPERS
FORMATTXT
FILE SIZE86 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC11662099

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