Non-obese non-alcoholic fatty liver disease and the risk of chronic kidney disease: a systematic review and meta-analysis

Yixian You, Xiong Pei, Wei Jiang, Qingmin Zeng, Lang Bai, Taoyou Zhou, Xiaoju Lv, Hong Tang, Dongbo Wu · 2024

Read Non-obese non-alcoholic fatty liver disease and the risk of chronic kidney disease: a systematic review and meta-analysis by Yixian You, Xiong Pei, Wei Jiang, Qingmin Zeng, Lang Bai, Taoyou Zhou, Xiaoju Lv, Hong Tang, Dongbo Wu (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11660860.txt.

Description

Yixian You and colleagues combined earlier studies in 2024 to compare kidney risk in fatty liver disease. Fatty liver is often tied to obesity, yet many patients are not obese. The open question was whether those leaner patients face less risk of later kidney disease than obese patients with the same liver problem. The team searched three major databases and pooled fifteen studies that tracked new kidney disease in both groups.

New kidney disease appeared at nearly the same rate in non-obese and obese patients. Two standard kidney function measures also showed no clear gap between the groups overall, though smaller differences appeared in some subgroups defined by region or test method. Splitting non-obese patients into normal-weight and overweight groups changed nothing. The authors warn that a healthy weight should not reassure doctors here, since fatty liver alone appears to carry the kidney risk.

Catalog record

CREATORYixian You, Xiong Pei, Wei Jiang, Qingmin Zeng, Lang Bai, Taoyou Zhou, Xiaoju Lv, Hong Tang, Dongbo Wu
YEAR2024
COLLECTIONPAPERS
FORMATTXT
FILE SIZE26 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC11660860

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