Lipopolysaccharide Effects on Neurotransmission: Understanding Implications for Depression
L. Batey, B. Baumberger, H. Khoshbouei, P. Hashemi · 2024
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Description
Batey and co-authors review how gut-wall toxin shifts brain chemistry in a 2024 perspective paper. Inflammation in the body and depression travel together, yet how body inflammation rewrites brain signals stayed murky. The toxin LPS, shed by bacteria, gives labs a fast, standard way to spark inflammation.
Across studies, the toxin lowered dopamine and serotonin in several brain zones while raising norepinephrine. The authors read this not as damage but as an evolved program: the body slows and turns inward to heal. Mood change, on this view, is part of the recovery script. The frame may reshape how depression with inflammation is understood.
Catalog record
| CREATOR | L. Batey, B. Baumberger, H. Khoshbouei, P. Hashemi |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 20 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |