Sterile activation of RNA-sensing pathways in autoimmunity
Jiaxin Li, Junyan Zhu, Hui Yang, Fajian Hou, Bing Su · 2024
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Description
The body's RNA alarms guard against viruses, but they can also fire on the body's own RNA by mistake. Jiaxin Li and co-authors review that friendly fire in a 2024 paper. When self RNA trips the alarms, the result can be lasting swelling and autoimmune disease.
The review gathers what sets off each sensor without any infection. It traces how those false alarms feed named diseases of the joints, skin, and other organs. It also weighs drugs that calm the sensors or their downstream signals. Some such drugs are in tests for autoimmune care. Knowing the triggers may help doctors pick who gets which drug.
Catalog record
| CREATOR | Jiaxin Li, Junyan Zhu, Hui Yang, Fajian Hou, Bing Su |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 72 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |