Time-dependent variation in immunoparalysis biomarkers among patients with sepsis and critical illness
Abigail Samuelsen, Erik Lehman, Parker Burrows, Anthony S. Bonavia · 2024
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Description
Abigail Samuelsen, Erik Lehman, Parker Burrows, and Anthony Bonavia track immune shutdown marks across the first two weeks of grave illness in a 2024 study. After sepsis or hard trauma, the immune system can go slack, a state that leaves patients open to fresh germs. Which marks best show that state, and when, was not clear.
The team drew blood from 64 grave patients, 31 with sepsis and 33 without, and fired the cells with test germs. One classic mark rose over time, but chiefly in the non-sepsis group. Cell counts healed more in the sepsis group. Two swelling signals rose in sepsis blood, while a third gave mixed reads by test type.
Catalog record
| CREATOR | Abigail Samuelsen, Erik Lehman, Parker Burrows, Anthony S. Bonavia |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 30 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |