The impact of glucose metabolism on inflammatory processes in sepsis-induced acute lung injury
Shilei Cheng, Yufei Li, Xiaoliang Sun, Zhirui Liu, Liang Guo, Jueheng Wu, Xiaohan Yang, Sisi Wei, Guanghan Wu, Shilong Xu, Fan Yang, Jianbo Wu · 2024
Read The impact of glucose metabolism on inflammatory processes in sepsis-induced acute lung injury by Shilei Cheng, Yufei Li, Xiaoliang Sun, Zhirui Liu, Liang Guo, Jueheng Wu, Xiaohan Yang, Sisi Wei, Guanghan Wu, Shilong Xu, Fan Yang, Jianbo Wu (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11659153.txt.
Description
Shilei Cheng and co-authors review research, published in 2024, on how sugar metabolism fuels lung injury during sepsis. Sepsis can trigger acute lung injury, a deadly complication whose mechanisms remain partly unclear. Immune cells such as macrophages rewire how they burn glucose as the illness unfolds, and that rewiring shapes the inflammation that harms the lung.
Early in the disease the new metabolic pattern feeds aggressive inflammation, while later it helps switch on calming responses, making it a double edged sword. The review tracks which cells rewire, which enzymes and intermediates control the switch, and where drugs might intervene. The authors aim to turn this metabolic map into better diagnosis and treatment for a condition with few options.
Catalog record
| CREATOR | Shilei Cheng, Yufei Li, Xiaoliang Sun, Zhirui Liu, Liang Guo, Jueheng Wu, Xiaohan Yang, Sisi Wei, Guanghan Wu, Shilong Xu, Fan Yang, Jianbo Wu |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 98 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |