Unravelling turbot (Scophthalmus maximus) resistance to Aeromonas salmonicida: transcriptomic insights from two full-sibling families with divergent susceptibility
Patricia Pereiro, Ricardo Tur, Miguel García, Antonio Figueras, Beatriz Novoa · 2024
Read Unravelling turbot (Scophthalmus maximus) resistance to Aeromonas salmonicida: transcriptomic insights from two full-sibling families with divergent susceptibility by Patricia Pereiro, Ricardo Tur, Miguel García, Antonio Figueras, Beatriz Novoa (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11659141.txt.
Description
Patricia Pereiro and co-authors published this study in 2024. It compares turbot fish families that resist or fall to a deadly bacterial disease. Furunculosis, caused by Aeromonas salmonicida, costs fish farms dearly and drives antibiotic use. Five sibling families were exposed to the germ. One family survived far better. The team then read gene activity in head kidney and liver, before and after infection, in the toughest and weakest families.
Even without infection, the families differed mainly in the liver. After infection, immune genes lit up in the head kidney. The resistant family kept its inflammation controlled and raised antigen-presentation and T-cell genes early. Many changed genes sat inside known resistance regions of the genome. The authors offer the signatures as breeding markers for hardier farmed fish.
Catalog record
| CREATOR | Patricia Pereiro, Ricardo Tur, Miguel García, Antonio Figueras, Beatriz Novoa |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 74 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |