The additive interaction of healthy lifestyles and genetic susceptibility on colorectal cancer risk in prediabetes: a large population-based prospective cohort study
Wenchen Wang, Yikang Cheng, Qingyu Meng, Baoqing Jia, Dawei Yao, Yiping Cheng · 2024
Read The additive interaction of healthy lifestyles and genetic susceptibility on colorectal cancer risk in prediabetes: a large population-based prospective cohort study by Wenchen Wang, Yikang Cheng, Qingyu Meng, Baoqing Jia, Dawei Yao, Yiping Cheng (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11658106.txt.
Description
Wenchen Wang and five co-authors report a 2024 cohort study on lifestyle, genes, and colorectal cancer risk in people with prediabetes. The team asked if a healthy way of life can offset a high genetic risk for this cancer in that group, and how the two forces add up.
Data came from more than twenty thousand UK Biobank members with prediabetes and no cancer at the start. Each person got a lifestyle score and a polygenic risk score, each split into grades. High genetic risk more than doubled cancer risk in the data. Models then test how the two scores act on each other.
Catalog record
| CREATOR | Wenchen Wang, Yikang Cheng, Qingyu Meng, Baoqing Jia, Dawei Yao, Yiping Cheng |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 48 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |