Significant association of miRNA 34a with BRCA1 expression in pancreatic ductal adenocarcinoma: an insight on miRNA regulatory pathways in the Pakistani population
Saleema Mehboob Ali, Yumna Adnan, Zubair Ahmad, Tabish Chawla, Hasnain Ahmed Farooqui, SM Adnan Ali · 2024
Read Significant association of miRNA 34a with BRCA1 expression in pancreatic ductal adenocarcinoma: an insight on miRNA regulatory pathways in the Pakistani population by Saleema Mehboob Ali, Yumna Adnan, Zubair Ahmad, Tabish Chawla, Hasnain Ahmed Farooqui, SM Adnan Ali (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11657824.txt.
Description
Saleema Mehboob Ali and co-authors study tiny gene regulators in 2024 in pancreatic cancer patients in Pakistan. Pancreatic cancer is among the deadliest cancers, and small RNA molecules help steer the signals that drive it. How four such regulators interact with key proteins in Pakistani patients had not been explored, so the team tested tumor samples from 109 patients.
Forty-three samples had RNA good enough for precise measurement. Three of the four small RNAs ran high in about seventy percent of cases. One of them linked strongly to levels of a well-known repair protein. Stains scored by two pathologists mapped the proteins in the same tumors. The study gives a first local picture of these regulatory pathways.
Catalog record
| CREATOR | Saleema Mehboob Ali, Yumna Adnan, Zubair Ahmad, Tabish Chawla, Hasnain Ahmed Farooqui, SM Adnan Ali |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 51 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |