Effective use of dupilumab for eosinophilic gastritis concomitant with severe asthma
Tomohito Takeshige, Ryo Koyama, Hiroaki Motomura, Akifumi Okajima, Toshihiko Nishioki, Junko Watanabe, Toshifumi Yae, Kenji Kido, Kazuhisa Takahashi · 2024
Read Effective use of dupilumab for eosinophilic gastritis concomitant with severe asthma by Tomohito Takeshige, Ryo Koyama, Hiroaki Motomura, Akifumi Okajima, Toshihiko Nishioki, Junko Watanabe, Toshifumi Yae, Kenji Kido, Kazuhisa Takahashi (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11656811.txt.
Description
Tomohito Takeshige and eight co-authors report a case where one drug eased two diseases at once. A thirty-five-year-old woman with severe asthma also developed eosinophilic gastritis, a rare condition where a type of white blood cell floods the stomach lining and causes pain. Approved treatments for the stomach condition are few. She came to hospital with worsening belly pain and a flare of her asthma.
Steroid treatment calmed her asthma but her belly pain stayed. A stomach biopsy confirmed the gastritis. Doctors started dupilumab, an antibody drug that blocks a shared signal for two allergy-linked messengers, aiming at her asthma with hope for the stomach too. Both conditions then improved: symptoms, blood tests, scope findings, and tissue samples all got better. No side effects appeared. The authors say the case supports the drug as an option when these two diseases occur together.
Catalog record
| CREATOR | Tomohito Takeshige, Ryo Koyama, Hiroaki Motomura, Akifumi Okajima, Toshihiko Nishioki, Junko Watanabe, Toshifumi Yae, Kenji Kido, Kazuhisa Takahashi |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 16 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |