Integrating bioinformatics and machine learning to uncover lncRNA LINC00269 as a key regulator in Parkinson's disease via pyroptosis pathways
LiLi Ma, Yue Liu, Yajing Ren, Na Mi, Jing Fang, Rui Bao, Xiuzhi Xu, Hongjia Zhang, Ying Tang · 2024
Read Integrating bioinformatics and machine learning to uncover lncRNA LINC00269 as a key regulator in Parkinson's disease via pyroptosis pathways by LiLi Ma, Yue Liu, Yajing Ren, Na Mi, Jing Fang, Rui Bao, Xiuzhi Xu, Hongjia Zhang, Ying Tang (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11656613.txt.
Description
LiLi Ma and co-authors hunt long non-coding RNAs that steer a fiery cell death path in Parkinson disease, in a study from two thousand twenty-four. Data from two public brain sets were mined with several learning methods. Two candidate RNAs stood out, and mouse brain tests checked the signals.
Cell death genes shifted in clear ways in the disease data, some up and some down. One candidate, LINC00269, fell sharply in the Parkinson mouse brain, backing its role. Links to four partner genes were also flagged for follow-up. The authors frame the RNA as a lead for new tests and drugs, not a proven cause. Readers get a vetted short list for lab work.
Catalog record
| CREATOR | LiLi Ma, Yue Liu, Yajing Ren, Na Mi, Jing Fang, Rui Bao, Xiuzhi Xu, Hongjia Zhang, Ying Tang |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 52 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |