Utility of 18F-Fluorodeoxyglucose Positron Emission Tomography in Evaluating Disseminated Nontuberculous Mycobacterial Infection in Patients With Anti-interferon-γ Autoantibodies

Pei-Ju Chuang, Wei-Cheng Lan, Mei-Fang Cheng, Chun-Kai Huang, Tzu-Chan Hong, Chi-Ying Lin, Yu-Shan Huang, Pao-Yu Chen, Un-In Wu, Jann-Tay Wang, Wang-Huei Sheng, Yee-Chun Chen, Shan-Chwen Chang · 2024

Read Utility of 18F-Fluorodeoxyglucose Positron Emission Tomography in Evaluating Disseminated Nontuberculous Mycobacterial Infection in Patients With Anti-interferon-γ Autoantibodies by Pei-Ju Chuang, Wei-Cheng Lan, Mei-Fang Cheng, Chun-Kai Huang, Tzu-Chan Hong, Chi-Ying Lin, Yu-Shan Huang, Pao-Yu Chen, Un-In Wu, Jann-Tay Wang, Wang-Huei Sheng, Yee-Chun Chen, Shan-Chwen Chang (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11656338.txt.

Description

Pei-Ju Chuang and twelve co-authors test PET scanning in a hard to manage infection in this 2024 paper. Their patients carry autoantibodies that neutralize interferon gamma, a key immune signal. That defect lets nontuberculous mycobacteria spread through the body. No settled guidance exists for treatment or prognosis. The team analyzed the first available FDG PET scans from a multicenter cohort. They asked what the scans predicted about returning to hospital within a year.

About forty-two percent of patients were rehospitalized in that window. One scan finding dominated: disease in the spleen raised the risk about eight fold. Other sites carried information too. Disease in chest nodes and in the spine's bones linked to slow growing mycobacteria species. The authors present the scan as a map that does triple duty: it stages the infection, hints at the species, and flags who needs the tightest follow up.

Catalog record

CREATORPei-Ju Chuang, Wei-Cheng Lan, Mei-Fang Cheng, Chun-Kai Huang, Tzu-Chan Hong, Chi-Ying Lin, Yu-Shan Huang, Pao-Yu Chen, Un-In Wu, Jann-Tay Wang, Wang-Huei Sheng, Yee-Chun Chen, Shan-Chwen Chang
YEAR2024
COLLECTIONPAPERS
FORMATTXT
FILE SIZE35 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC11656338

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