Gonadal hormone abnormalities in young patients with first-episode schizophrenia

Qiang Hu, Jindong Wang, Jing Liang, Meihong Xiu, Shuangli Zhang, Fengchun Wu · 2024

Read Gonadal hormone abnormalities in young patients with first-episode schizophrenia by Qiang Hu, Jindong Wang, Jing Liang, Meihong Xiu, Shuangli Zhang, Fengchun Wu (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11656025.txt.

Description

Sex hormones may help drive schizophrenia, and the earliest phase of the illness, before any drugs, is the cleanest place to look. Qiang Hu and co-authors measured five gonadal hormones in 2024 in 162 young patients with first-episode schizophrenia who had never taken antipsychotics, plus 74 healthy peers. They compared abnormal rates by sex.

Both male and female patients showed hormone disturbances at onset. A quarter of the men had abnormal estrogen levels, while the women showed raised rates of abnormality across four other hormones. Three hormone measures tied to the sex differences even after other factors were weighed. The authors frame the imbalance as part of the illness's onset and a lead for personalized care.

Catalog record

CREATORQiang Hu, Jindong Wang, Jing Liang, Meihong Xiu, Shuangli Zhang, Fengchun Wu
YEAR2024
COLLECTIONPAPERS
FORMATTXT
FILE SIZE26 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC11656025

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