Impact of prolactin treatment on enhancing the cellular responses of MCF7 breast cancer cells to tamoxifen treatment
Anwar Shams · 2024
Read Impact of prolactin treatment on enhancing the cellular responses of MCF7 breast cancer cells to tamoxifen treatment by Anwar Shams (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11655925.txt.
Description
Anwar Shams tests whether the hormone prolactin can make breast cancer cells answer better to the drug tamoxifen, in a 2024 study. Prolactin normally matures milk-producing tissue, and signs suggest it can also push cancer cells toward a calmer, more mature state. The work used MCF7, a standard estrogen-sensitive breast cancer cell line.
Pretreating the cells with prolactin clearly improved their sensitivity to tamoxifen in the reported experiments. The author frames the effect through differentiation: a cell pushed to mature may lose the flexibility that drives spread and drug resistance. The paper adds to the case that hormone-guided maturation deserves a place in breast cancer treatment research.
Catalog record
| CREATOR | Anwar Shams |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 53 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |