Rapid, multiplex and automated detection of bacteria and fungi in endophthalmitis via a microfluidic real-time pcr system
Siyu Wang, Yiteng Liu, Yingqi Li, Yibo Gao, Zhongliang Zou, Na Xu, Qi Song, Fangyan Liu, Yihong Song, Xian Wang, Zixin Fan · 2024
Read Rapid, multiplex and automated detection of bacteria and fungi in endophthalmitis via a microfluidic real-time pcr system by Siyu Wang, Yiteng Liu, Yingqi Li, Yibo Gao, Zhongliang Zou, Na Xu, Qi Song, Fangyan Liu, Yihong Song, Xian Wang, Zixin Fan (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11655742.txt.
Description
Siyu Wang and ten co-authors tested a chip-sized gene test for microbes inside an infected eye, in a study published in 2024. The disease is an emergency: sight hangs on a fast, correct identification of the microbe. Culture growth is slow and often misses. Their chip runs gene copying on a fluid card in about half an hour, once the DNA is drawn.
In 22 patients at two Chinese eye centers, the chip found the microbe in half the cases, a step past culture. Five cases were finds by the chip alone. Where culture did find a microbe, the chip agreed in full. The total wait ran far under both culture and deep gene sequencing. The authors present it as a fast in-house platform for eye wards.
Catalog record
| CREATOR | Siyu Wang, Yiteng Liu, Yingqi Li, Yibo Gao, Zhongliang Zou, Na Xu, Qi Song, Fangyan Liu, Yihong Song, Xian Wang, Zixin Fan |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 41 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |