Plasma metabolomics profiling of EGFR-mutant NSCLC patients treated with third-generation EGFR-TKI
Ning Lou, Ruyun Gao, Yuankai Shi, Xiaohong Han · 2024
Read Plasma metabolomics profiling of EGFR-mutant NSCLC patients treated with third-generation EGFR-TKI by Ning Lou, Ruyun Gao, Yuankai Shi, Xiaohong Han (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11655626.txt.
Description
Ning Lou, Ruyun Gao, Yuankai Shi, and Xiaohong Han share a data set in two thousand twenty-four on lung cancer patients and a targeted drug. The patients had EGFR-mutant non-small cell lung cancer and got a third-generation inhibitor drug. About thirty percent do not respond, and all eventually progress, yet no marker predicts who benefits.
The team profiled blood plasma metabolites with four mass spectrometry methods. Samples came from one hundred eighty-six patients before treatment, plus twenty after, covering over one thousand metabolites. Quality control was strict, and standard clinical measures did not differ between responders and non-responders. The data, posted for download, are meant to support work on metabolic response traits and personalized therapy.
Catalog record
| CREATOR | Ning Lou, Ruyun Gao, Yuankai Shi, Xiaohong Han |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 22 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |