Gene expression analysis of ovarian follicles and stromal cells in girls with Turner syndrome
Ron Peek, Sanne van der Coelen, Marie-Madeleine Dolmans · 2024
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Description
Three researchers study the ovaries of girls with Turner syndrome in a paper from 2024. Turner syndrome affects girls who are missing part or all of one X chromosome. Many have low fertility, and the team wanted to know why. They took small samples of ovary tissue during surgery from eight patients and eight girls without the condition.
The team sorted the tissue into egg follicles and the support cells around them, then compared gene activity. Support cells looked and acted much like normal cells. The follicles differed in eleven genes, and the active genes matched later stages of growth. The authors say this early shift may help explain the fertility problems.
Catalog record
| CREATOR | Ron Peek, Sanne van der Coelen, Marie-Madeleine Dolmans |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 40 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |